(Reuters Health), s\u1eed d\u1ee5ng c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf b\u01a1m proton (PPIs) c\u00f3 li\u00ean quan \u0111\u1ebfn gia t\u0103ng nguy c\u01a1 ph\u00e1t tri\u1ec3n ung th\u01b0 d\u1ea1 d\u00e0y b\u1ea5t k\u1ec3 t\u00ecnh tr\u1ea1ng ti\u1ec7t tr\u1eeb Helicobacter pylori, theo m\u1ed9t nghi\u00ean c\u1ee9u t\u1ea1i H\u00e0n Qu\u1ed1c.<\/p>\n\n\n\n
C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u \u0111\u00e3 ki\u1ec3m tra d\u1eef li\u1ec7u t\u1eeb d\u1ecbch v\u1ee5 b\u1ea3o hi\u1ec3m qu\u1ed1c gia H\u00e0n Qu\u1ed1c tr\u00ean 6877 b\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb b\u1eb1ng PPI v\u00e0 6877 b\u1ec7nh nh\u00e2n \u1edf nh\u00f3m ch\u1ee9ng ph\u00f9 h\u1ee3p c\u00f3 xu h\u01b0\u1edbng kh\u00f4ng s\u1eed d\u1ee5ng PPI. Theo d\u00f5i trung b\u00ecnh trong 4.4 n\u0103m \u1edf nh\u00f3m s\u1eed d\u1ee5ng PPI c\u00f3 118 b\u1ec7nh nh\u00e2n \u0111\u00e3 ph\u00e1t tri\u1ec3n ung th\u01b0 d\u1ea1 d\u00e0y, so v\u1edbi 40 tr\u01b0\u1eddng h\u1ee3p ung th\u01b0 d\u1ea1 d\u00e0y \u1edf nh\u00f3m kh\u00f4ng s\u1eed d\u1ee5ng PPI khi theo d\u00f5i trung b\u00ecnh trong 4.2 n\u0103m.<\/p>\n\n\n\n
So v\u1edbi nh\u00f3m kh\u00f4ng s\u1eed d\u1ee5ng PPI, c\u00e1c b\u1ec7nh nh\u00e2n s\u1eed dung PPI trong 30 ng\u00e0y c\u00f3 nguy c\u01a1 ph\u00e1t tri\u1ec3n ung th\u01b0 d\u1ea1 d\u00e0y cao h\u01a1n \u0111\u00e1ng k\u1ec3 (t\u1ef7 s\u1ed1 r\u1ee7i ro 2.37)<\/p>\n\n\n\n
Ngo\u00e0i ra c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u c\u0169ng ph\u00e1t hi\u1ec7n th\u1ea5y m\u1ed9t nh\u00f3m nh\u1ecf c\u00e1c b\u1ec7nh nh\u00e2n b\u1ecb nhi\u1ec5m H. pylori m\u1ea1n t\u00ednh \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb ti\u1ec7t tr\u1eeb c\u00f3 nguy c\u01a1 ph\u00e1t tri\u1ec3n ung th\u01b0 d\u1ea1 d\u00e0y nhi\u1ec1u h\u01a1n \u0111\u00e1ng k\u1ec3 n\u1ebfu h\u1ecd s\u1eed d\u1ee5ng PPIs trong 180 ng\u00e0y tr\u1edf l\u00ean so v\u1edbi n\u1ebfu h\u1ecd kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c (t\u1ef7 s\u1ed1 r\u1ee7i ro HR 2.22)<\/p>\n\n\n\n
Li\u1ec7u ph\u00e1p ti\u1ec7t tr\u1eeb H. pylori \u0111\u01b0\u1ee3c \u00e1p d\u1ee5ng cho 2.9% b\u1ec7nh nh\u00e2n c\u00f3 s\u1eed d\u1ee5ng PPI v\u00e0 2.5% b\u1ec7nh nh\u00e2n kh\u00f4ng s\u1eed d\u1ee5ng PPI trong nghi\u00ean c\u1ee9u.<\/p>\n\n\n\n
M\u1ed9t h\u1ea1n ch\u1ebf c\u1ee7a nghi\u00ean c\u1ee9u n\u00e0y l\u00e0 c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u \u0111\u00e3 thi\u1ebfu d\u1eef li\u1ec7u v\u1ec1 t\u00ecnh tr\u1ea1ng nhi\u1ec5m H. pylori v\u00e0 c\u00e1c k\u1ebft qu\u1ea3 x\u00e9t nghi\u1ec7m nhanh urease v\u00e0 ure trong h\u01a1i th\u1edf \u0111\u1ec3 x\u00e1c nh\u1eadn t\u00ecnh tr\u1ea1ng ti\u1ec7t tr\u1eeb, c\u00e1c t\u00e1c gi\u1ea3 l\u01b0u \u00fd tr\u00ean Gut (Gut \u1edf \u0111\u00e2y c\u00f3 th\u1ec3 l\u00e0 m\u1ed9t t\u1ea1p ch\u00ed v\u1ec1 ti\u00eau h\u00f3a – Gut, a leading international journal from BMJ and BSG, publishes cutting-edge gastroenterology and hepatology research). T\u00e1c gi\u1ea3 ch\u00ednh Dr. Woon Geon Shin t\u1eeb B\u1ec7nh vi\u1ec7n Th\u00e1nh T\u00e2m Kangdong and \u0110\u1ea1i h\u1ecdc y khoa Hallym, Seoul, H\u00e0n Qu\u1ed1c \u0111\u00e3 kh\u00f4ng h\u1ed3i \u0111\u00e1p c\u00e1c y\u00eau c\u1ea7u tr\u1ea3 l\u1eddi.<\/p>\n\n\n\n
C\u0169ng c\u00f3 th\u1ec3 nh\u00f3m s\u1eed d\u1ee5ng PPI c\u00f3 nhi\u1ec1u b\u1ec7nh nh\u00e2n b\u1ecb nhi\u1ec5m H. pylori v\u00e0 lo\u00e9t d\u1ea1 d\u00e0y n\u1eb7ng h\u01a1n nh\u00f3m kh\u00f4ng s\u1eed d\u1ee5ng PPI v\u00ec PPI ki\u1ec3m so\u00e1t pH d\u1ea1 d\u00e0y v\u01b0\u1ee3t tr\u1ed9i h\u01a1n c\u00e1c li\u1ec7u ph\u00e1p thay th\u1ebf kh\u00e1c, Ruben Abagyan, gi\u00e1o s\u01b0 d\u01b0\u1ee3c t\u1ea1i \u0110\u1ea1i h\u1ecdc California, San Diego, ng\u01b0\u1eddi kh\u00f4ng tham gia v\u00e0o nghi\u00ean c\u1ee9u cho bi\u1ebft.<\/p>\n\n\n\n
Do \u0111\u00f3, ung th\u01b0 d\u1ea1 d\u00e0y xu\u1ea5t hi\u1ec7n nhi\u1ec1u h\u01a1n c\u00f3 th\u1ec3 do h\u1eadu qu\u1ea3 c\u1ee7a t\u00ecnh tr\u1ea1ng n\u1ec1n li\u00ean quan \u0111\u1ebfn \u0111i\u1ec1u tr\u1ecb h\u01a1n l\u00e0 do \u0111i\u1ec1u tr\u1ecb, Abagyan cho bi\u1ebft qua email.<\/p>\n\n\n\n
M\u1eb7c d\u00f9 v\u1eady, c\u00e1c b\u00e1c s\u0129 l\u00e2m s\u00e0ng n\u00ean bi\u1ebft r\u1eb1ng b\u1ea3n th\u00e2n vi\u1ec7c lo\u1ea1i tr\u1eeb H. pylori kh\u00f4ng \u0111\u1ee7 \u0111\u1ec3 ng\u0103n ng\u1eeba ho\u00e0n to\u00e0n ung th\u01b0 d\u1ea1 d\u00e0y, Abagyan n\u00f3i.<\/p>\n\n\n\n
\u201cC\u00e1c v\u1ebft lo\u00e9t \u1edf \u0111\u01b0\u1eddng ti\u00eau h\u00f3a l\u00e0 v\u1ebft lo\u00e9t h\u1edf d\u1eabn \u0111\u1ebfn t\u00ecnh tr\u1ea1ng vi\u00eam m\u00e3n t\u00ednh li\u00ean t\u1ee5c v\u00e0 th\u01b0\u1eddng xuy\u00ean, l\u00e0m t\u0103ng nguy c\u01a1 ung th\u01b0 \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, nguy c\u01a1 n\u00e0y c\u00f3 th\u1ec3 t\u0103ng l\u00ean do nhi\u1ec5m tr\u00f9ng; tuy nhi\u00ean, nhi\u1ec5m tr\u00f9ng kh\u00f4ng ph\u1ea3i l\u00e0 th\u1ee7 ph\u1ea1m ch\u00ednh”<\/p>\n\n\n\n
https://www.medscape.com\/viewarticle\/951571<\/code><\/pre>\n\n\n\n . <\/p>\n","protected":false},"excerpt":{"rendered":"
(Reuters Health), s\u1eed d\u1ee5ng c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf b\u01a1m proton (PPIs) c\u00f3 li\u00ean quan \u0111\u1ebfn gia t\u0103ng nguy c\u01a1 ph\u00e1t tri\u1ec3n ung th\u01b0 d\u1ea1 d\u00e0y<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2,41],"tags":[65,66],"class_list":["post-653","post","type-post","status-publish","format-standard","hentry","category-doc-sach-cho-vui","category-english-corner","tag-ppi","tag-ung-thu-da-day"],"_links":{"self":[{"href":"https:\/\/cdha.edu.vn\/cdha\/wp-json\/wp\/v2\/posts\/653","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cdha.edu.vn\/cdha\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cdha.edu.vn\/cdha\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cdha.edu.vn\/cdha\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cdha.edu.vn\/cdha\/wp-json\/wp\/v2\/comments?post=653"}],"version-history":[{"count":3,"href":"https:\/\/cdha.edu.vn\/cdha\/wp-json\/wp\/v2\/posts\/653\/revisions"}],"predecessor-version":[{"id":657,"href":"https:\/\/cdha.edu.vn\/cdha\/wp-json\/wp\/v2\/posts\/653\/revisions\/657"}],"wp:attachment":[{"href":"https:\/\/cdha.edu.vn\/cdha\/wp-json\/wp\/v2\/media?parent=653"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cdha.edu.vn\/cdha\/wp-json\/wp\/v2\/categories?post=653"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cdha.edu.vn\/cdha\/wp-json\/wp\/v2\/tags?post=653"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}